Functions as an E3-type small ubiquitin-like modifier (SUMO) ligase, stabilizing the interaction between UBE2I and the substrate, and as a SUMO-tethering ...
由 G Gill 著作 · 2004 · 被引用 995 次 — Similar to nonproteolytic roles of ubiquitin, SUMO modification regulates protein localization and activity. Some proteins can be modified by SUMO and ubiquitin ...
In molecular biology, SUMO (Small Ubiquitin-like Modifier) proteins are a family of small proteins that are covalently attached to and detached from other ...
SUMOs are small Ub-related modifier proteins found in all eukaryotes. Even though the amino acid sequence similarity between Ub (76 amino acids, ∼9 kDa) and ...
由 TY Yau 著作 · 2021 · 被引用 31 次 — SUMO modulates protein function through covalent conjugation to lysine residues in a large number of proteins. Once covalently conjugated to a ...
由 HY Ryu 著作 · 2020 · 被引用 22 次 — The SUMO protein posttranslationally modifies diverse substrates involved in various cellular processes, including transcription, DNA ...
由 PMV Shetty 著作 · 2020 · 被引用 15 次 — SUMO is a conserved family of proteins that has one member in yeast, around eight in plants and four in mammals. In the late 90s, a single ...
由 AB Celen 著作 · 2020 · 被引用 140 次 — Small ubiquitin-like modifier (SUMO) is a highly conserved, ubiquitin-like small protein that can be attached to protein substrates to increase ...
